Analysis Note

ControlHuman IgG, Human IgG Fab Fragment, Human IgG Fc, Human IgM Fc, Human IgM (myeloma) Fab m fragment, Human IgA, Mouse IgM, Rat IgM whole molecule, Chicken IgM whole molecule, Goat IgM whole molecule, Guinea Pig IgM whole molecule, Hamster IgM whole molecule, and Rabbit IgM whole molecule

Application

Research Sub CategoryIsotype Control Antibodies

Research CategorySecondary & Control Antibodies

Sheep anti-Human IgM, (Fc) Antibody is an antibody against Human IgM, (Fc) for use in ELISA.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Immunoglobin M (IgM) antibody is prominent in early immune responses to most antigens and is the predominant response in certain antibody responses such as "natural" blood group antibodies. IgM is the major immunoglobin expressed on surface B lymphocytes. Most of the chronic lymphocytic leukemias, non Hodgkin lymphomas and Burkitt′s lymphoma bear surface IgM, whereas plasmocytes from Waldenström′s disease bear intracytoplasmic IgM.

Immunogen

Human anti-Human IgM (myeloma) Fc5u fragment

Epitope: IgM, (Fc)

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Format: Purified

Purified sheep polyclonal in PBS containing 0.05% sodium azide. Depleted against rabbit IgM and human IgG.

Depletion

Quality

Evaluated by ELISA against Human IgG, Human IgG Fab Fragment, Human IgG Fc, Human IgM Fc, Human IgM (myeloma) Fab m fragment, Human IgA, Mouse IgM, Rat IgM whole molecule, Chicken IgM whole molecule, Goat IgM whole molecule, Guinea Pig IgM whole molecule, Hamster IgM whole molecule, and Rabbit IgM whole molecule.

ELISA Analysis: A representative lot detected Sheep Anti-Human IgM, (Fc) in ELISA.

Specificity

This antibody reacts with human IgM, (Fc) as demonstrated by ELISA.

No reactivity with IgG or IgA. May react with IgM of other species with low specificity.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

50 kDa calculated